Weight Loss Motivation

Weight Loss Motivation Blog

Instant Gratification for Weight Loss - Try Turkey Walk

Ever wonder what it feels like to lose 15 lbs or 30 lbs instantly? Ever wonder what it feels like to lug extra 15 lbs or 30 lbs around all the time?

You can feel it with the Turkey Walk.

Friday, December 28, 2007

Obesity Weakens Immune System

Obese people find it harder to fight infections, and a weakened immune response may be to blame, suggests a new study from Boston University researchers.

In experiments with mice infected with the bacteria Porphyromonas gingivalis, obese mice had less ability to battle gum infection than their normal-weight counterparts, according to the report in this week's early online edition of the Proceedings of the National Academy of Sciences.

"For years, we have had difficulty understanding why obese people have difficulty clearing an infection," said lead researcher Dr. Salomon Amar, associate dean for research at the university's School of Dental Medicine.

"Now we understand that dysfunction in some of the mechanisms, as a result of the obesity, explain difficulty in clearing the infection and also the difficulty in wound healing," Amar said.

In the study, Amar's team tied silk threads infected with the bacteria around the molars of obese and normal-weight mice. They then compared the animals' responses to infection, by measuring both the amount of bone loss and the growth of the bacteria around their teeth.

The researchers found that the obese mice had a compromised immune response to the bacteria, which made the animals more susceptible to the infection.

Amar's group also looked at the animals' white blood cells, which are the main line of defense against infection. The white cells of obese mice had lower levels of an important signaling molecule, and some of the genes that fight inflammation were altered, the researchers found.

The same mechanism is at work in humans, Amar added. In fact, studies in obese
people have shown they are more likely to have gum disease than non-obese people. The disease is caused by bacteria, which causes inflammation and destruction of the bone underlying teeth.

Amar thinks that obese people need to be treated differently to help them fight infections. "We need to be more aggressive in the use of targeted antibiotics in infections among obese people," he said. "Also, we need to boost the immune response." Quoted from this article


Our health is often the reflection of the state of our immune system. Can you live a healthy life with all the extra weight? When was the last time you came across an obese individual who was very healthy? It is no surprise the unhealthiness of being overweight or obese results from a compromised immune system.

Given all the infectious diseases caused by bacteria and viruses, being obese not only put the obese individuals in danger, but also people around them because the likelihood their carrying and spreading of the infectious agents.

0 Comments:

Post a Comment